Kv3 channels can offer the dominant current that repolarizes presynaptic action potentials even when other currents, like Kv1 and Ca2+-activated BK currents, are also readily detected in voltage-clamp experiments that use a traditional rectangular voltage command. This can be the circumstance while in the terminals of glutamatergic mossy fibers tha
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5c–d). CX-5461-mediated S33 phosphorylation of RPA was impartial with the cell cycle phase and wasn't restricted for the nucleoli in HR-deficient cells. Thus, the development of ssDNA structures in CX-5461 taken care of cells may result in replication fork stalling and ATR activation with HRD exacerbating CX-5461-mediated replication worry and
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